Persistent fasting triglycerides >880 mg/dL? It could be familial chylomicronemia 
syndrome (FCS).16,12

Acute pancreatitis.

Recurrent, unexplained abdominal pain. 

Eruptive xanthomas.

These are just a few signs of FCS.12

Familial chylomicronemia syndrome (FCS) is a rare genetic 
condition characterized by fasting chylomicronemia, extremely high triglyceride levels (≥880 mg/dL),12 and resistance to traditional 
TG-lowering medication.16

Despite the genetic nature of FCS, its recessive inheritance pattern means many people with FCS have no family history of the condition.14

An estimated 1-13 people per million 
have FCS.45, 46,47

Due to this rarity, some healthcare professionals may find the clinical features of FCS challenging to recognize and diagnose. Diagnostic delays can leave people with FCS at a very high risk for severe complications, such as acute pancreatitis (AP) and hepatosplenomegaly.34 For AP alone, they have a 360-fold elevated risk compared with the general population.14

In addition, FCS dramatically impairs quality of life, well-being, social relationships, and ability to maintain employment.22