Resources

Stay Informed Download the Genetic Testing for FCS flyer and CORE Clinical Trials Fact Sheet
Stay Informed Download the Genetic Testing for FCS flyer and CORE Clinical Trials Fact Sheet

Videos

Associated Risks of Unmanaged Elevated Triglycerides

Baylor College of Medicine cardiologist Dr. Christie Ballantyne explains the associated health risks of unmanaged elevated triglycerides.

Duration: 1 minute 22 seconds
Duration: 1 minute 21 seconds
Duration: 1 minute 9 seconds

Associated Health Risks for People Living with Severe Hypertriglyceridemia (sHTG)

Endocrinologist Dr. Robert Eckel, Professor of Medicine Emeritus at the University of Colorado School of Medicine, explains the associated health risks for people living with severe hypertriqlyceridemia (SHTG).

What is the importance of researching apolipoprotein C3 (apoC-Il) inhibition for severe hypertriqlyceri-demia (sHTGI?
Duration: 54 seconds

Suggested Articles and Organizations Focused on High Triglycerides

Ginsberg HN, Packard CJ, Chapman MJ, et al. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society. Eur Heart J. 2021;42(47):4791-4806.

Virani SS, Morris PB, Agarwala A, et al. 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2021.

Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. Lancet. 2014;384(9943):626-635.

Laufs U, Parhofer KG, Ginsberg HN, et al. Clinical review on triglycerides. Eur Heart J. 2020;41(1):99-109c.

Hegele RA, Ginsberg HN, Chapman MJ, et al. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol. 2014;2(8):655-666.

Nordestgaard BG. Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease: New Insights From Epidemiology, Genetics, and Biology. Circ Res. 2016;118(4):547-563.

Professional
Associations

National Lipid Association

NLA offers a “Find a Member” feature to assist locating a lipid specialist in your area.

www.lipid.org

American College of Cardiology

The ACC provides education, credentials. policy support, and research for the cardiovascular community.

www.ACC.org

European Atherosclerosis Society

EAS offers guidelines and educational programs about managing lipid disorders.

www.EAS-Society.org

National Lipid Association

NLA offers a “Find a Member” feature to assist locating a lipid specialist in your area.

www.lipid.org

European Atherosclerosis Society

EAS offers guidelines and educational programs about managing liquid disorders.

www.EAS-Society.org

International Atherosclerosis Society

IAS represents 67 national organizations in 57 countries and works to improve implementation of guidelines related to atherosclerosis.

www.Athero.org

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    SHOW REFERENCES

    1. Ginsberg HN, Packard CJ, Chapman MJ, et al. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society. Eur Heart J. 2021;42(47):4791-4806.

    2. Virani SS, Morris PB, Agarwala A, et al. 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2021.

    3. Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. Lancet. 2014;384(9943):626-635.

    4. Laufs U, Parhofer KG, Ginsberg HN, et al. Clinical review on triglycerides. Eur Heart J. 2020;41(1):99-109c.

    5. Packard CJ. Remnants, LDL, and the Quantification of Lipoprotein-Associated Risk in Atherosclerotic Cardiovascular Disease. Curr Atheroscler Rep. 2022;24(1534-6242 (Electronic)):133-142.

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    20. Nordestgaard BG, Benn M, Schnohr P, et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. Jama. 2007;298(3):299-308.

    21. Stroes E, Moulin P, Parhofer KG, et al. Diagnostic algorithm for familial chylomicronemia syndrome. Atheroscler Suppl. 2017;23:1-7.

    22. Davidson M, Stevenson M, Hsieh A, et al. The burden of familial chylomicronemia syndrome: Results from the global IN-FOCUS study. J Clin Lipidol. 2018;12(4):898-907.e892.

    23. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2019;73(24):e285-e350.

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    27. Koehler EM, Schouten JN, Hansen BE, et al. External validation of the fatty liver index for identifying nonalcoholic fatty liver disease in a population-based study. Clin Gastroenterol Hepatol. 2013;11(9):1201-1204.

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    35. ClinicalTrials.gov A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia. ClinicalTrials.gov identifier: NCT05610280. Accessed March 13, 2023. Updated March 1, 2023. https://clinicaltrials.gov/ct2/show/NCT05610280